Belharra’s Searchlight™ Platform illuminates novel, functionally relevant binding pockets on elusive, high-value drug targets across the entire undrugged proteome. As the most unbiased chemoproteomics platform in the industry, Searchlight can find any binding pocket, in any protein or protein complex, in any cell type.
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Why are so many proteins considered undruggable?
Most drugs take hold of crevices or pockets in a protein’s structure. Not all proteins have binding pockets that are accessible or even static.
Without an identifiable pocket, the industry struggles to develop a small molecule therapy that can latch on and change the course of the disease – making the protein target “undruggable.”
PICTURED:
Yvonne Schmidt, Ph.D.
Director, Medicinal Chemistry
Changing the Human Experience
At Belharra, we envision a world where the entire proteome is druggable and no disease is untreatable.
