Belharra’s Bedrock: Solid Science
Our approach to drug discovery is founded on over a decade of design and evolution of photoaffinity-based chemoproteomic chemistries.
Read about the scientific findings that helped build our technology.
Ligand and Target Discovery by Fragment-Based Screening in Human Cells
Cell. 2017 January 26; 168(3): 527–541.e29. doi:10.1016/j.cell.2016.12.029
Expedited Mapping of the Ligandable Proteome Using Fully Functionalized Enantiomeric Probe Pairs
Nat Chem. 2019 December ; 11(12): 1113–1123. doi:10.1038/s41557-019-0351-5
Evaluation of Fully-Functionalized Diazirine Tags for Chemical Proteomic Applications
Chem. Sci., 2021, 12, 7839